A new experimental platform facilitates assessment of the transcriptional and chromatin landscapes of aging yeast
Replicative aging of Saccharomyces cerevisiae is an established model system for eukaryotic cellular aging.A limitation in yeast lifespan studies has been the difficulty of separating old cells from young cells in large quantities.We engineered a new platform, the Smoking Accessories Miniature-chemostat Aging Device (MAD), that enables purification